Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.76 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.73 |
| ▸ | KDM4A | O75164 | 2/20 | 0.73 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.73 |
| ▸ | KDM6B | O15054 | 1/20 | 0.73 |
| ▸ | KDM6A | O15550 | 1/20 | 0.73 |
| ▸ | TET3 | O43151 | 1/20 | 0.73 |
| ▸ | KDM4B | O94953 | 1/20 | 0.73 |
| ▸ | KDM5C | P41229 | 1/20 | 0.73 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.73 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.73 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.73 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.73 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.73 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.73 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.73 |
| ▸ | COMT | P21964 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7650578 | 0.98 | KDM4E (0.97) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL11159839 | 0.86 | KDM4E (1.00) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL27468637 | 0.86 | KDM4E (0.77) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL6068195 | 0.84 | KDM4E (1.00) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL29349767 | 0.84 | KDM4E (1.00) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL163474 | 0.83 | KDM4E (0.73) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL29462403 | 0.83 | KDM4E (0.73) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL11803066 | 0.82 | KDM4E (0.68) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| Hydrochloric Acid SCHEMBL3310696 | 0.81 | KDM4E (0.71) | KDM4EL3MBTL1FTOKDM4AEGLN1 | |
| SCHEMBL10157045 | 0.79 | KDM4E (0.67) | KDM4EL3MBTL1FTOKDM4AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495336-B1 | OLIGOPEPTIDE DERIVATIVES WHOSE C-TERMINAL AMINO ACID IS ARGININE WHICH IS LINKED TO THE REMAINDER OF AN ELECTROACTIVE ANILINE OR AMINOQUINILONE; SUBSTRATE FOR QUANTITATIVELY DETERMINING ENZYMES, ESPECIALLY THROMBIN, IN BLOOD | PENTAPHARM AG (CH) | 2002-12-17 | — | — | US | claimed |
| EP-3609868-B1 | TETRAHYDROQUINOLINE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2023-10-18 | — | — | EP | disclosed |