Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 5/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064705 | 0.86 | GRN (0.49) | GRNSORT1RAB9APOLBKMT2A | |
| SCHEMBL3750397 | 0.82 | POLB (0.54) | RAB9ANPC1ATMCNR2CNR1 | |
| SCHEMBL13475471 | 0.81 | GRN (0.50) | GRNSORT1RAB9APOLBCACNA1H | |
| SCHEMBL8400220 | 0.79 | GRN (0.47) | GRNSORT1RAB9AFABP4CACNA1H | |
| SCHEMBL19656295 | 0.77 | CNR2 (0.46) | RAB9ANPC1ATMCNR2CNR1 | |
| SCHEMBL2759010 | 0.76 | NPC1 (0.61) | RAB9ANPC1ATMCNR2CNR1 | |
| SCHEMBL8402006 | 0.76 | GRN (0.47) | GRNSORT1RAB9AATMPOLB | |
| SCHEMBL18285323 | 0.76 | CNR2 (0.45) | RAB9ANPC1ATMCNR2CNR1 | |
| SCHEMBL29727654 | 0.76 | CNR2 (0.45) | RAB9ANPC1ATMCNR2CNR1 | |
| SCHEMBL29727678 | 0.76 | CNR2 (0.45) | RAB9ANPC1ATMCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402411-B | Oxidation reaction-based synthesis method of propyzamide | 深圳市谦陌通辰实验有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-113402411-A | Oxidation reaction-based synthesis method of propyzamide | 深圳市谦陌通辰实验有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-113402411-B | Oxidation reaction-based synthesis method of propyzamide | 深圳市谦陌通辰实验有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-113402411-A | Oxidation reaction-based synthesis method of propyzamide | 深圳市谦陌通辰实验有限公司 | 2021-09-17 | — | — | CN | disclosed |