Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 5/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520220 | 0.90 | CACNA1H (0.45) | GRNSORT1FABP4CYP2D6KCNH2 | |
| SCHEMBL8400220 | 0.87 | GRN (0.47) | GRNSORT1FABP4CYP2D6KCNH2 | |
| SCHEMBL8399956 | 0.86 | L3MBTL1 (0.49) | KCNH2RAB9AMEN1CYP2C19KMT2A | |
| SCHEMBL8400109 | 0.85 | GRN (0.46) | GRNSORT1FABP4CYP2D6KCNH2 | |
| SCHEMBL14184751 | 0.84 | POLB (0.37) | CYP2D6MEN1CYP1A2CYP3A4GAA | |
| SCHEMBL7530423 | 0.83 | GRN (0.43) | GRNSORT1FABP4CYP2D6KCNH2 | |
| SCHEMBL8399960 | 0.83 | GRN (0.43) | GRNSORT1FABP4CYP2D6KCNH2 | |
| SCHEMBL8400274 | 0.83 | GRN (0.44) | GRNSORT1FABP4CYP2D6KCNH2 | |
| SCHEMBL8404905 | 0.81 | GRN (0.43) | GRNSORT1FABP4CYP2D6KCNH2 | |
| SCHEMBL8404914 | 0.80 | DDR1 (0.43) | GRNSORT1FABP4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859063-A | Use of certain N-acetonylbenzamides as fungicides | ROHM AND HAAS COMPANY (US) | 1999-01-12 | — | — | US | disclosed |
| US-5629346-A | LOW TOXICITY | ROHM AND HAAS COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| US-4822902-A | LOW PHYTOTOXICITY | ROHM AND HAAS COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0173453-B1 | SUBSTITUTED N-ACETONYLBENZAMIDES AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1988-07-13 | — | — | EP | disclosed |
| EP-0173453-A1 | Substituted N-acetonylbenzamides and their use as fungicides | ROHM AND HAAS COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |