SCHEMBL28625916

SCHEMBL28625916

CC(=O)c1ccc(C2CC(=O)c3ccc(O)cc3O2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.78
TUBB4A P04350 1/20 0.78
TUBB P07437 1/20 0.78
YES1 P07947 1/20 0.78
TUBA3C P0DPH7 1/20 0.78
TUBA1B P68363 1/20 0.78
TUBA4A P68366 1/20 0.78
TUBB4B P68371 1/20 0.78
TUBB3 Q13509 1/20 0.78
TUBB2A Q13885 1/20 0.78
TUBB8 Q3ZCM7 1/20 0.78
TUBA3E Q6PEY2 1/20 0.78
TUBA1A Q71U36 1/20 0.78
ESR2 Q92731 1/20 0.78
TUBA1C Q9BQE3 1/20 0.78
TUBB6 Q9BUF5 1/20 0.78
TUBB2B Q9BVA1 1/20 0.78
TUBB1 Q9H4B7 1/20 0.78
MAOB P27338 4/20 0.71
MAOA P21397 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28629171 0.91 MAOB (0.62) CYP19A1TUBB4ATUBBYES1TUBA3C
Liquirtigenin SCHEMBL74552 0.88 CYP19A1 (1.00) CYP19A1TUBB4ATUBBYES1TUBA3C
Liquirtigenin SCHEMBL26970367 0.88 CYP19A1 (1.00) CYP19A1TUBB4ATUBBYES1TUBA3C
Liquirtigenin SCHEMBL1071066 0.88 CYP19A1 (1.00) CYP19A1TUBB4ATUBBYES1TUBA3C
Liquirtigenin SCHEMBL29552383 0.88 CYP19A1 (1.00) CYP19A1TUBB4ATUBBYES1TUBA3C
Liquirtigenin SCHEMBL30352791 0.88 CYP19A1 (1.00) CYP19A1TUBB4ATUBBYES1TUBA3C
Liquirtigenin SCHEMBL16240337 0.87 CYP19A1 (0.86) CYP19A1TUBB4ATUBBYES1TUBA3C
SCHEMBL17709031 0.86 CYP19A1 (0.72) CYP19A1TUBB4ATUBBYES1TUBA3C
SCHEMBL17709030 0.86 CYP19A1 (0.72) CYP19A1TUBB4ATUBBYES1TUBA3C
Liquirtigenin SCHEMBL4649862 0.86 CYP19A1 (0.97) CYP19A1TUBB4ATUBBYES1TUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112661738-B Flavanone compound and preparation method and application thereof 南方医科大学 2023-01-10 CN disclosed
CN-112661738-A Flavanone compound and preparation method and application thereof 南方医科大学 2021-04-16 CN disclosed