⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862589 | 1.00 | — | — | |
| SCHEMBL13118698 | 1.00 | — | — | |
| SCHEMBL28440391 | 0.69 | — | — | |
| SCHEMBL9249509 | 0.69 | — | — | |
| SCHEMBL9249500 | 0.69 | — | — | |
| SCHEMBL13118674 | 0.69 | — | — | |
| SCHEMBL2715061 | 0.67 | — | — | |
| Formic Acid SCHEMBL135127 | 0.63 | — | — | |
| Formic Acid SCHEMBL16108323 | 0.63 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL39520 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312203-A1 | Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors | WYETH (US) | 2008-12-18 | — | — | US | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-102020659-B | Preparation method of methylal penem intermediate | SINOCHEM CORP | 2013-07-03 | — | — | CN | disclosed |
| CN-102020615-B | Morpholone derivative and preparation method thereof | SINOCHEM CORP | 2012-08-29 | — | — | CN | disclosed |
| CN-102020658-B | 2-chloro-6, 8-dihydro-5H-imidazo [2,1-c ] - [1,4] oxazine and preparation method thereof | SINOCHEM CORP | 2012-05-23 | — | — | CN | disclosed |
| CN-102020615-A | Morpholone derivative and preparation method thereof | SINOCHEM CORP | 2011-04-20 | — | — | CN | disclosed |
| CN-102020659-A | Preparation method of methylal penem intermediate | SINOCHEM CORP | 2011-04-20 | — | — | CN | disclosed |
| CN-102020658-A | Novel compound and preparation method thereof | SINOCHEM CORP | 2011-04-20 | — | — | CN | disclosed |
| US-7812014-B2 | Bicyclic 6-alkylidene-penems as β-lactamase inhibitors | WYETH LLC (US) | 2010-10-12 | — | — | US | disclosed |
| CN-1649883-B | Bicyclic 6-alkylidene-epimycotenes as lactamase inhibitors | WYETH CORP | 2010-05-26 | — | — | CN | disclosed |
| EP-1513818-A2 | HETEROCYCLIC INHIBITORS OF KINASES | Bristol-Myers Squibb Company (US) | 2005-03-16 | — | — | EP | disclosed |
| EP-1499620-A1 | PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES | Wyeth (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1499621-A1 | BICYCLIC 6-ALKYLIDENE-PENEMS AS BETA-LACTAMASES INHIBITORS | Wyeth (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20040132708-A1 | Process for preparing 6-alkylidene penem derivatives | WYETH | 2004-07-08 | — | — | US | disclosed |
| US-20040077622-A1 | Bicyclic 5-alkylidene-penems as beta lactamases inhibitors | WYETH | 2004-04-22 | — | — | US | disclosed |
| US-20040077696-A1 | Heterocyclic inhibitors of kinases | BRISTOL-MYERS SQUIBB COMPANY | 2004-04-22 | — | — | US | disclosed |
| US-20040053913-A1 | Process for preparing 6-alkylidene penem derivatives | WYETH | 2004-03-18 | — | — | US | disclosed |
| WO-2004001059-A2 | HETEROCYCLIC INHIBITORS OF KINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |
| WO-2003093277-A1 | PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES | WYETH (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003093279-A1 | BICYCLIC 6-ALKYLIDENE-PENEMS AS ß-LACTAMASES INHIBITORS | WYETH (US) | 2003-11-13 | — | — | WO | disclosed |