Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268 | 0.99 | KMT2A (0.68) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL16613223 | 0.89 | KMT2A (0.56) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL21350911 | 0.88 | KMT2A (0.57) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL16598061 | 0.88 | KMT2A (0.57) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL3299372 | 0.87 | KMT2A (0.68) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL537642 | 0.86 | CHRNA7 (0.60) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL18542682 | 0.86 | KMT2A (0.54) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL537295 | 0.85 | KMT2A (0.56) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL22896893 | 0.84 | KMT2A (0.65) | KMT2AGAAMAPTPOLBTP53 | |
| SCHEMBL2835335 | 0.84 | KMT2A (0.65) | KMT2AGAAMAPTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108147996-B | Synthetic method of arylmethylene bispyrazole ester monopotassium salt | 扬州大学 | 2021-09-24 | — | — | CN | disclosed |