SCHEMBL28626494

SCHEMBL28626494

Cc1cc(C(=O)O)ccc1CCN1C(=O)CSC1c1ccc(F)cc1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 18/20 0.63
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28626118 0.90 HTR7 (0.66) HTR7MEN1KMT2A
SCHEMBL28645435 0.82 HTR7 (0.58) HTR7
SCHEMBL28641043 0.81 HTR7 (0.49) HTR7MEN1KMT2A
SCHEMBL28625950 0.80 HTR7 (0.56) HTR7
SCHEMBL28634730 0.79 HTR7 (0.66) HTR7MEN1KMT2A
SCHEMBL28629819 0.79 HTR7 (0.67) HTR7MEN1KMT2A
SCHEMBL28638518 0.78 HTR7 (0.58) HTR7
SCHEMBL28627426 0.78 MEN1 (0.67) HTR7MEN1KMT2A
SCHEMBL28625935 0.78 HTR7 (0.67) HTR7MEN1KMT2A
SCHEMBL19305928 0.78 HTR7 (1.00) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108883099-B Thiazolidinone compounds and use thereof 石全 2021-09-28 CN disclosed