Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791411 | 0.70 | TSHR (0.50) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL27811962 | 0.69 | ACHE (0.48) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL3289373 | 0.69 | TSHR (0.48) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL29597934 | 0.67 | TSHR (0.46) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL10308658 | 0.67 | TSHR (0.46) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL23005901 | 0.65 | PPARD (0.40) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL575839 | 0.65 | TSHR (0.50) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL13657439 | 0.65 | TSHR (0.50) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL9115350 | 0.65 | TSHR (0.50) | TP53TDP1TSHRACHEPPARD | |
| SCHEMBL12207660 | 0.65 | TSHR (0.43) | TP53TDP1TSHRACHEPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283647-A | Prodrug modulators that integrate stress pathways | 卡里科生命科学有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-113423685-B | Prodrug modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-113423685-A | Prodrug modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-09-21 | — | — | CN | disclosed |