Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870042 | 0.81 | ABCC8 (0.39) | ABCC8KCNJ11 | |
| SCHEMBL2868146 | 0.80 | ABCC8 (0.47) | ABCC8KCNJ11 | |
| SCHEMBL3260729 | 0.68 | ABCC8 (0.43) | ABCC8KCNJ11MEN1KMT2A | |
| SCHEMBL12852342 | 0.67 | ABCC8 (0.50) | ABCC8KCNJ11KMT2A | |
| SCHEMBL2862045 | 0.67 | ABCC8 (0.50) | ABCC8KCNJ11KMT2A | |
| SCHEMBL11270561 | 0.61 | MEN1 (0.50) | MEN1KMT2ACCNCCDK8CDK19 | |
| SCHEMBL16075241 | 0.61 | MAPT (0.42) | MEN1KMT2AEEF2K | |
| SCHEMBL29178523 | 0.60 | GRM2 (0.44) | — | |
| SCHEMBL3506164 | 0.59 | KDM4E (0.69) | ABCC8KCNJ11MEN1KMT2A | |
| SCHEMBL2643948 | 0.59 | CYP1A2 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3612223-B1 | TREATING MALE SENESCENCE | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2024-07-31 | — | — | EP | claimed |
| CN-103641795-A | Acetophenone derivatives containing 1,2,3-thiadiazole and preparation method and use thereof | UNIV NANKAI | 2014-03-19 | — | — | CN | claimed |
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | NIHON NOHYAKU CO., LTD. (JP) | 2008-08-21 | — | — | US | claimed |
| CN-101128445-A | 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same | NIHON NOHYAKU CO LTD (JP) | 2008-02-20 | — | — | CN | claimed |
| EP-1852428-A1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | claimed |
| EP-1852428-B1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2012-05-16 | — | — | EP | disclosed |
| CN-101128445-B | 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same | NIHON NOHYAKU CO LTD | 2012-01-18 | — | — | CN | disclosed |
| US-7786040-B2 | 4-cyclopropyl-1,2,3,-thiadiazole compound, agrohorticultural plant disease controlling agent and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | NIHON NOHYAKU CO., LTD. (JP) | 2008-08-21 | — | — | US | disclosed |
| CN-101128445-A | 4-cyclopropyl-1,2,3-thiadiazole derivative, agrohorticultural plant disease controlling agent, and method for using the same | NIHON NOHYAKU CO LTD (JP) | 2008-02-20 | — | — | CN | disclosed |
| EP-1852428-A1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | CBR3, CBR1, OSR1 | ABCC8 1005/4885KCNJ11 1207/4885MEN1 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.