Methane

Methane

SCHEMBL28626702

C.C=CCC(OC(CC=C)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GSR P00390 1/20 0.34
SLC6A4 P31645 2/20 0.33
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL939842 0.98 CYP2C19 (0.50) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL8680427 0.85 CYP2C19 (0.50) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL27547164 0.82 CYP2C19 (0.52) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL18236072 0.82 SMN1; SMN2 (0.47) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL6200840 0.82 SMN1; SMN2 (0.47) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL28422465 0.82 CYP2C19 (0.47) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL369647 0.82 CYP2C19 (0.47) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL22654158 0.81 CYP2C19 (0.40) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL7760225 0.80 CYP2C19 (0.46) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT
Hydrochloric Acid SCHEMBL7234524 0.80 SMN1; SMN2 (0.46) CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651553-B Strong-alkaline composite ion exchange resin material and preparation method thereof 中国石油化工股份有限公司 2021-09-03 CN disclosed