⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652 | 0.73 | — | — | |
| SCHEMBL2886819 | 0.71 | — | — | |
| SCHEMBL3367366 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL3366779 | 0.70 | — | — | |
| SCHEMBL3701152 | 0.68 | — | — | |
| SCHEMBL1173523 | 0.68 | — | — | |
| SCHEMBL4392232 | 0.68 | — | — | |
| SCHEMBL6140833 | 0.68 | CYP2C19 (0.31) | — | |
| SCHEMBL11088558 | 0.68 | — | — | |
| SCHEMBL6141553 | 0.68 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142671-A2 | MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS | Qiagen GmbH (DE) | 2010-01-13 | — | — | EP | claimed |
| WO-2008119539-A2 | MODIFIED POLYNUCLEOTIDES COMPRISING RIBOSE RINGS | QIAGEN GMBH (DE) | 2008-10-09 | — | — | WO | claimed |
| EP-1196631-A1 | POLYNUCLEOTIDES | Cyclops Genome Sciences Limited (GB) | 2002-04-17 | — | — | EP | claimed |
| WO-2001094626-A1 | POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2001-12-13 | — | — | WO | claimed |
| WO-2000075306-A2 | METHOD FOR PRODUCING DOUBLE STRANDED POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2000-12-14 | — | — | WO | claimed |
| WO-2000066605-A2 | POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2000-11-09 | — | — | WO | claimed |
| US-5541189-A | Substituted aliphatic amine-containing macrocyclic immunomodulators | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | claimed |
| US-5457194-A | Immunosuppressants | ABBOTT LABORATORIES (US) | 1995-10-10 | — | — | US | claimed |
| EP-3169698-A1 | NOVEL COMPOUNDS | The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of Holy and Undiv. Trinity of Queen Elizabeth near Dublin (IE) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016008946-A1 | NOVEL COMPOUNDS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2016-01-21 | — | — | WO | disclosed |
| WO-2009002746-A1 | DOSING SCHEDULES OF LEUKOTRIENE SYNTHESIS INHIBITORS FOR HUMAN THERAPY | DECODE GENETICS EHF. (IS) | 2008-12-31 | — | — | WO | disclosed |
| EP-1896028-A2 | SUSTAINED RELEASE FORMULATION AND DOSING SCHEDULES OF LEUKOTRIENE SYNTHESIS INHIBITOR FOR HUMAN THERAPY | Decode Genetics EHF. (IS) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006116349-A2 | SUSTAINED RELEASE FORMULATION AND DOSING SCHEDULES OF LEUKOTRIENE SYNTHESIS INHIBITOR FOR HUMAN THERAPY | DECODE GENETICS EHF. (IS) | 2006-11-02 | — | — | WO | disclosed |
| EP-1196631-A1 | POLYNUCLEOTIDES | Cyclops Genome Sciences Limited (GB) | 2002-04-17 | — | — | EP | disclosed |
| US-5457194-A | Immunosuppressants | ABBOTT LABORATORIES (US) | 1995-10-10 | — | — | US | disclosed |
| WO-1994021634-A1 | SUBSTITUTED ALICYCLIC-ALIPHATIC AMINE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |
| WO-1994021254-A1 | SUBSTITUTED ALICYCLIC AMINE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |
| WO-1994021253-A1 | SUBSTITUTED ALIPHATIC AMINE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0292808-A2 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0284954-A2 | Cephalosporinderivatives, process for their preparation and their use in pharmaceutical products | BAYER AG (DE) | 1988-10-05 | — | — | EP | disclosed |