Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 4/20 | 0.36 |
| ▸ | GABRD | O14764 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.36 |
| ▸ | GABRE | P78334 | 4/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4393165 | 0.89 | GABRP (0.36) | FFAR3LCKFYNSLC7A5TSHR | |
| Butanedione SCHEMBL27424811 | 0.88 | TSHR (0.44) | SLC7A5TSHRGABRPGABRDGABRA1 | |
| Acetic Acid SCHEMBL28636093 | 0.82 | CA1 (0.44) | SLC7A5TSHRLMNAALOX15BLM | |
| Acetic Acid SCHEMBL27732782 | 0.81 | — | — | |
| Acetic Acid SCHEMBL670655 | 0.79 | FFAR3 (0.58) | FFAR3LCKFYNSLC7A5TSHR | |
| Acetic Acid SCHEMBL27717337 | 0.79 | FFAR3 (0.58) | FFAR3LCKFYNSLC7A5TSHR | |
| Acetic Acid SCHEMBL44094 | 0.79 | — | — | |
| Acetic Acid SCHEMBL28157960 | 0.79 | — | — | |
| SCHEMBL55913 | 0.79 | — | — | |
| SCHEMBL8330698 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278676-A | Serum sodium detection reagent and gamma-glutamyl transferase detection reagent | 深圳市锦瑞生物科技有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-113278676-A | Serum sodium detection reagent and gamma-glutamyl transferase detection reagent | 深圳市锦瑞生物科技有限公司 | 2021-08-20 | — | — | CN | disclosed |