⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31742511 | 0.90 | — | — | |
| SCHEMBL12334240 | 0.90 | — | — | |
| SCHEMBL15497510 | 0.86 | — | — | |
| SCHEMBL12533148 | 0.83 | — | — | |
| SCHEMBL10983150 | 0.80 | — | — | |
| SCHEMBL5263481 | 0.79 | — | — | |
| SCHEMBL6739662 | 0.78 | — | — | |
| SCHEMBL3043216 | 0.76 | — | — | |
| SCHEMBL107094 | 0.76 | TAS1R3 (0.33) | — | |
| SCHEMBL24984112 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107750250-B | Indolone compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-09-07 | — | — | CN | disclosed |