SCHEMBL28627161

SCHEMBL28627161

CC1(c2cc(Br)cc(Br)c2)CC(c2ccccc2)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.40
KDM1A O60341 4/20 0.33
MAOA P21397 4/20 0.33
MAOB P27338 4/20 0.33
HTR2A P28223 1/20 0.33
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28623848 0.87 SIGMAR1 (0.40) SIGMAR1KDM1AMAOAMAOBHTR2A
SCHEMBL28615808 0.78 SIGMAR1 (0.40) SIGMAR1
SCHEMBL28615619 0.75 KDM1A (0.43) SIGMAR1KDM1AHTR2A
SCHEMBL28025960 0.73 SIGMAR1 (0.49) SIGMAR1KDM1AMAOAMAOBHTR2A
SCHEMBL11205351 0.68 SIGMAR1 (0.41) SIGMAR1KDM1AMAOAMAOBHTR2A
SCHEMBL23795263 0.66 MAPT (0.35) SIGMAR1
SCHEMBL4582810 0.65 SIGMAR1 (0.47) SIGMAR1MAOAMAOBHTR2A
SCHEMBL10546397 0.65 SIGMAR1 (0.41) SIGMAR1KDM1AMAOAMAOBHTR2A
SCHEMBL11796945 0.64 SIGMAR1 (0.46) SIGMAR1MAOAMAOBHTR2A
SCHEMBL14701152 0.63 MEN1 (0.45) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113365976-A Diphenylindane, triphenylindane and tetraphenylindan derivatives and their use in organic devices 多蒂肯独家合成控股公司 2021-09-07 CN disclosed