Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 16/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879337 | 0.98 | PTPN11 (0.36) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL29802932 | 0.96 | PTPN11 (0.36) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL21631652 | 0.80 | PTPN11 (0.36) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL23508730 | 0.78 | PTPN11 (0.37) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL21653696 | 0.76 | ADORA2A (0.42) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL26156073 | 0.76 | PTPN11 (0.36) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL21631725 | 0.75 | ADORA2A (0.38) | PTPN11ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL26920421 | 0.75 | PTPN11 (0.35) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL24858186 | 0.74 | MET (0.35) | PTPN11ADORA2AADORA1KDM4ENSD2 | |
| SCHEMBL28889827 | 0.74 | PTPN11 (0.36) | PTPN11ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981268-A | Pyrimidine-4 (3H) -ketone heterocyclic compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113135910-A | Pyrimidine-4 (3H) -ketone heterocyclic compound, preparation method and pharmaceutical application thereof | 北京诺诚健华医药科技有限公司 | 2021-07-20 | — | — | CN | disclosed |