SCHEMBL28627699

SCHEMBL28627699

OC(Cc1ccc(OC(F)(F)F)cc1)C(O)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.43
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
EPHX1 P07099 2/20 0.41
CASR P41180 1/20 0.40
PTPN1 P18031 1/20 0.40
SLC6A4 P31645 1/20 0.40
EPHX2 P34913 2/20 0.40
PPARG P37231 2/20 0.40
PPARA Q07869 2/20 0.40
PDE2A O00408 1/20 0.40
FPR2 P25090 1/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 1/20 0.39
CETP P11597 1/20 0.39
DAO P14920 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5751556 0.79 CASR (0.44) ACACBEPHX1CASRPTPN1EPHX2
SCHEMBL28729244 0.79 PDE2A (0.42) CASRSLC6A4EPHX2PDE2AALDH1A1
SCHEMBL16563529 0.77 CETP (0.50) ACACBESR1ESR2EPHX1PTPN1
SCHEMBL28620628 0.77 CYP2D6 (0.58) SLC6A4PPARGPPARA
SCHEMBL1416925 0.77 ACACB (0.52) ACACBEPHX1CASRPTPN1SLC6A4
SCHEMBL5753436 0.76 PTPN1 (0.44) ACACBEPHX1CASRPTPN1EPHX2
SCHEMBL22816220 0.76 ACACB (0.45) ACACBEPHX1CASRPTPN1SLC6A4
SCHEMBL12706130 0.76 CYP1A2 (0.61) ACACBESR1ESR2EPHX1PTPN1
SCHEMBL1721415 0.75 PDE2A (0.51) ACACBEPHX1SLC6A4EPHX2PDE2A
SCHEMBL28615738 0.75 PDE2A (0.51) EPHX1SLC6A4EPHX2PDE2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641831-B Monomers, polymers, preparation method and use thereof 东莞东阳光医疗智能器件研发有限公司 2021-09-10 CN disclosed