Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721415 | 0.89 | PDE2A (0.51) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL1046494 | 0.84 | PDE2A (0.54) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL18291828 | 0.84 | PDE2A (0.54) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL17996536 | 0.82 | PDE2A (0.46) | PDE2AALDH1A1MAPTEPHX2CYP17A1 | |
| SCHEMBL17996561 | 0.82 | PDE2A (0.50) | PDE2AALDH1A1L3MBTL1CYP17A1CYP2C9 | |
| SCHEMBL16771224 | 0.79 | PDE2A (0.49) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL2056155 | 0.79 | PDE2A (0.58) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL84428 | 0.79 | ALDH1A1 (0.65) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL646362 | 0.79 | TOP2A (0.49) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 | |
| SCHEMBL28729244 | 0.78 | PDE2A (0.42) | PDE2AALDH1A1MAPTEPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641831-B | Monomers, polymers, preparation method and use thereof | 东莞东阳光医疗智能器件研发有限公司 | 2021-09-10 | — | — | CN | disclosed |