Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 4/20 | 0.49 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12346562 | 0.90 | LSS (0.60) | LSSDRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL12733053 | 0.89 | LSS (0.58) | LSSQDPRDRD2CHKA | |
| SCHEMBL15417746 | 0.84 | LSS (0.50) | LSSQDPRDRD2DRD3SLC6A2 | |
| SCHEMBL14544198 | 0.78 | RAB9A (0.50) | LSSQDPRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23134213 | 0.77 | LSS (0.60) | LSSDRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14320804 | 0.77 | SLC18A3 (0.46) | LSSQDPRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8082343 | 0.77 | LSS (0.60) | LSSDRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL999428 | 0.77 | BRD4 (0.50) | LSSQDPRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21815500 | 0.77 | BRD4 (0.50) | LSSQDPRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13416053 | 0.77 | NPC1 (0.47) | LSSQDPRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-28 | — | — | CN | disclosed |