Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638782 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL20489824 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL20489821 | 0.81 | KDM4E (0.54) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL245424 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL29416984 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL22223316 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL1943866 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL29611929 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL19952870 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1POLBFDPS | |
| SCHEMBL18810213 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1POLBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-28 | — | — | CN | disclosed |