SCHEMBL28628330

SCHEMBL28628330

[CH2]C(CCCC[C@@H](N)C(=O)N1CCC(NC(=O)NC)CC1)OC

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 7/20 0.41
EPHX2 P34913 10/20 0.39
DPP8 Q6V1X1 2/20 0.36
DPP9 Q86TI2 2/20 0.36
KDM5A P29375 1/20 0.35
EPHX1 P07099 2/20 0.34
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Carbamate SCHEMBL28611639 0.83 METAP1 (0.43) DPP7EPHX2DPP8DPP9KDM5A
SCHEMBL28624310 0.82 EPHX2 (0.48) DPP7EPHX2EPHX1
SCHEMBL28624308 0.82 EPHX2 (0.48) DPP7EPHX2EPHX1
SCHEMBL28611637 0.82 DPP7 (0.41) DPP7EPHX2DPP8DPP9KDM5A
SCHEMBL20873024 0.82 DPP7 (0.41) DPP7EPHX2DPP8DPP9KDM5A
SCHEMBL28613201 0.81 EPHX2 (0.44) DPP7EPHX2DPP8DPP9KDM5A
SCHEMBL28613203 0.81 EPHX2 (0.44) DPP7EPHX2DPP8DPP9KDM5A
SCHEMBL28581493 0.78 DPP7 (0.37) DPP7EPHX2DPP8DPP9KDM5A
SCHEMBL28581494 0.78 EPHX1 (0.46) DPP7EPHX2DPP8DPP9EPHX1
SCHEMBL19708437 0.78 EPHX1 (0.46) DPP7EPHX2DPP8DPP9EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107098871-B Phenyl propionamide derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2021-07-02 CN disclosed