Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29274947 | 0.79 | ALDH1A1 (0.43) | NPC1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9544174 | 0.75 | ALDH1A1 (0.47) | NPC1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL15078018 | 0.75 | EPHX2 (0.39) | EPHX2ALDH1A1HTTMEN1KMT2A | |
| Bromide SCHEMBL9763941 | 0.74 | ALDH1A1 (0.46) | NPC1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL30843869 | 0.73 | EPHX2 (0.36) | NPC1EPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL17675109 | 0.70 | ALDH1A1 (0.40) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL17675112 | 0.70 | SCN10A (0.40) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2221293 | 0.70 | POLB (0.52) | NPC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1003996 | 0.70 | POLB (0.52) | NPC1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27840443 | 0.69 | POLB (0.35) | ALDH1A1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994402-A | Antibodies to PMEL17 and conjugates thereof | 诺华股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118955718-A | Antibody drug conjugates and methods of making the same | 诺华股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-113195541-B | Antibodies to PMEL17 and conjugates thereof | 诺华股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118420766-A | Antibodies to PMEL17 and conjugates thereof | 诺华股份有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-113195541-A | Antibodies against PMEL17 and conjugates thereof | 诺华股份有限公司 | 2021-07-30 | — | — | CN | disclosed |