SCHEMBL28628599

SCHEMBL28628599

Nc1c(Br)ccnc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30398249 1.00
Cyanide SCHEMBL27963976 0.93 MEN1 (0.33)
SCHEMBL6711366 0.79
SCHEMBL29562566 0.79
SCHEMBL7887262 0.79
SCHEMBL29374917 0.79
SCHEMBL6172813 0.75
SCHEMBL2596902 0.75
SCHEMBL1967648 0.75
SCHEMBL22465644 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260107629-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-04-16 US disclosed
CN-116171155-A Pyrido [2,3-d ] pyrimidine-2 (1H) -ketone derivative, preparation method and application thereof 上海和誉生物医药科技有限公司 2023-05-26 CN disclosed
WO-2022121839-A1 PYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海和誉生物医药科技有限公司 2022-06-16 WO disclosed
CN-113166065-A Compounds and compositions for treating conditions associated with NLRP activity 诺华股份有限公司 2021-07-23 CN disclosed