SCHEMBL1967648

SCHEMBL1967648

Nc1c(Cl)ccnc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30783153 1.00
SCHEMBL413011 0.77
SCHEMBL29486472 0.77
SCHEMBL28628599 0.75
SCHEMBL3678352 0.75
SCHEMBL30398249 0.75
SCHEMBL29374917 0.75
SCHEMBL7887262 0.75
SCHEMBL1056076 0.75
SCHEMBL29479544 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3901151-B1 HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2026-04-01 EP disclosed
US-12590102-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2026-03-31 US disclosed
EP-3643713-B1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-07-30 EP disclosed
US-20250101015-A1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-03-27 US disclosed
US-20250084076-A1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-03-13 US disclosed
US-12172993-B2 Heterocyclic kinase inhibitors and uses thereof IOMX THERAPEUTICS AG (DE) 2024-12-24 US disclosed
US-12139480-B2 5-thiazolecarboxamide kinase inhibitor and uses thereof IOMX THERAPEUTICS AG (DE) 2024-11-12 US disclosed
CN-115190879-B Novel compound and organic light emitting device comprising the same 株式会社LG化学 2024-04-30 CN disclosed
CN-114845997-B Aromatic compound and application thereof in preparation of antitumor drugs 上海喆邺生物科技有限公司 2024-03-29 CN disclosed
US-20240101573-A1 MACROCYCLIC K-RAS G12C INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF ABBISKO THERAPEUTICS CO., LTD. (CN) 2024-03-28 US disclosed
EP-1257276-A4 ANTIVIRAL AZAINDOLE DERIVATIVES BRISTOL MYERS SQUIBB CO (US) 2004-10-27 EP disclosed
US-20040023982-A1 Antiviral azaindole derivatives VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) 2004-02-05 US disclosed
US-6632819-B1 HIV and AIDS BRISTOL-MYERS SQUIBB COMPANY 2003-10-14 US disclosed
US-20030181463-A1 Antiviral azaindole derivatives VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) 2003-09-25 US disclosed
CN-1404392-A Antiviral azaindole derivatives BRISTOL MYERS SQUIBB CO (US) 2003-03-19 CN disclosed
EP-1257276-A1 ANTIVIRAL AZAINDOLE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-11-20 EP disclosed
US-6476034-B2 AIDS THERAPY BRISTOL-MYERS SQUIBB COMPANY 2002-11-05 US disclosed
US-20020119982-A1 Antiviral azaindole derivatives VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) 2002-08-29 US disclosed
US-20020061892-A1 Antiviral azaindole derivatives VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) 2002-05-23 US disclosed
WO-2001062255-A1 ANTIVIRAL AZAINDOLE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2001-08-30 WO disclosed