Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272138 | 0.91 | KMT2A (0.56) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL3955084 | 0.88 | KMT2A (0.61) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL5511867 | 0.88 | KMT2A (0.54) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL10584268 | 0.87 | KMT2A (0.64) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL7417826 | 0.87 | KMT2A (0.52) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL7342649 | 0.87 | KMT2A (0.52) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL7207882 | 0.85 | KMT2A (0.51) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL11615752 | 0.85 | KMT2A (0.51) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL27182378 | 0.85 | KMT2A (0.51) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB | |
| SCHEMBL27958259 | 0.85 | KMT2A (0.51) | KMT2AALDH1A1SMN1; SMN2CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456215-B | Functional diamine monomer with high planarity and containing fluorene or fluorenone structure as well as synthesis method and application thereof | 湖南工业大学 | 2021-10-01 | — | — | CN | disclosed |