Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207882 | 0.99 | KMT2A (0.51) | KMT2AALDH1A1TDP1CYP3A4POLB | |
| SCHEMBL27182378 | 0.99 | KMT2A (0.51) | KMT2AALDH1A1TDP1CYP3A4POLB | |
| SCHEMBL27958259 | 0.99 | KMT2A (0.51) | KMT2AALDH1A1TDP1CYP3A4POLB | |
| SCHEMBL11615752 | 0.99 | KMT2A (0.51) | KMT2AALDH1A1TDP1CYP3A4POLB | |
| SCHEMBL5511867 | 0.96 | KMT2A (0.54) | KMT2AALDH1A1TDP1CYP3A4POLB | |
| SCHEMBL6272138 | 0.90 | KMT2A (0.56) | KMT2AALDH1A1TDP1CYP3A4POLB | |
| SCHEMBL22124694 | 0.87 | ALDH1A1 (0.51) | KMT2AALDH1A1TDP1CYP3A4MEN1 | |
| SCHEMBL28628640 | 0.87 | KMT2A (0.63) | KMT2AALDH1A1TDP1CYP3A4POLB | |
| SCHEMBL8094971 | 0.86 | ALDH1A1 (0.49) | KMT2AALDH1A1TDP1POLBMEN1 | |
| SCHEMBL8092479 | 0.86 | ALDH1A1 (0.49) | KMT2AALDH1A1TDP1POLBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819113-B1 | BENZAMIDES FOR NEURODEGENERATIVE DISORDER TREATMENT | CENTAUR PHARMACEUTICALS INC (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1079820-A1 | BENZAMIDE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999059569-A1 | BENZAMIDE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-25 | — | — | WO | disclosed |
| CN-1218399-A | Benzamide treatment of dementia associated with AIDs virus (HIV-4) infection | CENTAUR PHARMACEUTICALS INC (US) | 1999-06-02 | — | — | CN | disclosed |