Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727194 | 0.81 | PDE4B (0.41) | HTR6HTR2AHTR2C | |
| SCHEMBL28629784 | 0.81 | CYP2A6 (0.35) | SLC2A1KMT2AKRAS | |
| SCHEMBL28625221 | 0.73 | BRD4 (0.53) | BRD4SLC2A1HTR2AHTR2C | |
| SCHEMBL26613868 | 0.70 | PDE4B (0.38) | — | |
| SCHEMBL30633765 | 0.70 | PDE4B (0.38) | — | |
| SCHEMBL16751949 | 0.70 | KRAS (0.44) | KRAS | |
| SCHEMBL15825284 | 0.69 | GSK3B (0.39) | HTR6 | |
| SCHEMBL30686150 | 0.69 | GSK3B (0.39) | HTR6 | |
| SCHEMBL26675188 | 0.68 | HTR2A (0.39) | HTR6HTR2A | |
| SCHEMBL16751928 | 0.67 | LMNA (0.45) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402515-B | Indole compound and preparation method and application thereof | 四川大学华西医院 | 2022-05-27 | — | — | CN | disclosed |
| CN-113402515-A | Indole compound and preparation method and application thereof | 四川大学华西医院 | 2021-09-17 | — | — | CN | disclosed |