Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631658 | 0.83 | CYP19A1 (0.37) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL4621667 | 0.81 | CTSB (0.35) | — | |
| SCHEMBL10700783 | 0.77 | CYP19A1 (0.41) | CYP19A1UGT1A4PDE4DTACR1 | |
| SCHEMBL10702682 | 0.77 | CYP19A1 (0.41) | CYP19A1UGT1A4PDE4DTACR1 | |
| SCHEMBL10703762 | 0.77 | CYP19A1 (0.41) | CYP19A1UGT1A4PDE4DTACR1 | |
| SCHEMBL10701617 | 0.75 | CYP19A1 (0.39) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL1172829 | 0.75 | CYP19A1 (0.42) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL4621304 | 0.73 | ESR1 (0.41) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL3238041 | 0.73 | CYP19A1 (0.75) | CYP19A1UGT1A4PDE4D | |
| SCHEMBL10701541 | 0.72 | CYP19A1 (0.31) | CYP19A1UGT1A4PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997236-B | Preparation method of anastrozole impurity | 重庆华邦制药有限公司 | 2021-09-14 | — | — | CN | disclosed |