Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893806 | 1.00 | FFAR1 (0.36) | FFAR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL8651599 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMAPTIMPDH2 | |
| SCHEMBL1778656 | 0.76 | MEN1 (0.42) | ALDH1A1KDM4EGAAMAPTPGR | |
| SCHEMBL29893809 | 0.75 | PTPN1 (0.36) | FFAR1GAAMAPTPTGDR2MEN1 | |
| SCHEMBL29894671 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTCXCR2CXCR1TSHR | |
| SCHEMBL12408477 | 0.69 | FFAR1 (0.59) | FFAR1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL30468202 | 0.69 | FFAR1 (0.47) | FFAR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL2466535 | 0.69 | FFAR1 (0.47) | FFAR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL29894046 | 0.68 | CA12 (0.33) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL31235647 | 0.67 | MEN1 (0.43) | ALDH1A1CXCR2CXCR1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121542-B | 5, 10-indolino [3,2-b ] indole derivative and synthetic method and application thereof | 常州大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113372258-A | Indeno [1,2-b ] indole derivative and preparation method and application thereof | 常州大学 | 2021-09-10 | — | — | CN | disclosed |
| CN-113121542-A | 5, 10-indolino [3,2-b ] indole derivative and synthesis method and application thereof | 常州大学 | 2021-07-16 | — | — | CN | disclosed |