SCHEMBL28629345

SCHEMBL28629345

N#CCCOC(=O)c1ccccc1O.c1cc2cc-2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
SERPINE1 P05121 1/20 0.42
RAB9A P51151 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
TSHR P16473 3/20 0.41
KDM4E B2RXH2 2/20 0.41
GAA P10253 1/20 0.41
ATM Q13315 1/20 0.41
LMNA P02545 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
ALDH1A1 P00352 3/20 0.41
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 2/20 0.41
GSTA1 P08263 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621204 0.91 TDP1 (0.67) TDP1SERPINE1RAB9AL3MBTL1TSHR
SCHEMBL10430717 0.82 ALDH1A1 (0.58) TDP1RAB9AL3MBTL1TSHRKDM4E
SCHEMBL6063013 0.77 TDP1 (0.85) TDP1SERPINE1RAB9AL3MBTL1TSHR
SCHEMBL30416074 0.77 TDP1 (0.85) TDP1SERPINE1RAB9AL3MBTL1TSHR
SCHEMBL10430715 0.76 ALDH1A1 (0.56) TDP1RAB9AL3MBTL1TSHRKDM4E
SCHEMBL9178035 0.76 ALDH1A1 (0.47) TDP1L3MBTL1TSHRALDH1A1HTT
SCHEMBL9765812 0.73 TDP1 (0.92) TDP1SERPINE1RAB9AL3MBTL1TSHR
SCHEMBL12083356 0.73 TDP1 (1.00) TDP1SERPINE1RAB9AL3MBTL1TSHR
SCHEMBL5411025 0.72 ALDH1A1 (0.44) TDP1RAB9AL3MBTL1TSHRKDM4E
SCHEMBL15402 0.72 TDP1 (0.76) TDP1SERPINE1RAB9AL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113088013-A UVC-resistant ASA resin composition and preparation method thereof 上海金山锦湖日丽塑料有限公司 2021-07-09 CN claimed
CN-114773743-B UVC-resistant HIPS resin composition and preparation method thereof 上海金山锦湖日丽塑料有限公司 2024-04-23 CN disclosed
CN-116218155-A Flame-retardant PCTG resin composition and preparation method and application thereof 上海锦湖日丽塑料有限公司 2023-06-06 CN disclosed
CN-114773743-A UVC-resistant HIPS resin composition and preparation method thereof 上海金山锦湖日丽塑料有限公司 2022-07-22 CN disclosed
CN-113088013-B UVC-resistant ASA resin composition and preparation method thereof 上海金山锦湖日丽塑料有限公司 2022-07-15 CN disclosed
CN-113088013-A UVC-resistant ASA resin composition and preparation method thereof 上海金山锦湖日丽塑料有限公司 2021-07-09 CN disclosed