Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629542 | 1.00 | KDM4E (0.41) | KDM4EPDK1SMN1; SMN2USP2HPGD | |
| SCHEMBL16081469 | 0.80 | ACKR3 (0.53) | KDM4ESMN1; SMN2USP2HPGDTP53 | |
| SCHEMBL16034970 | 0.80 | USP2 (0.44) | KDM4EPDK1SMN1; SMN2USP2ACKR3 | |
| SCHEMBL16034971 | 0.80 | USP2 (0.44) | KDM4EPDK1SMN1; SMN2USP2ACKR3 | |
| SCHEMBL21069382 | 0.80 | PDK1 (0.41) | KDM4EPDK1ACKR3ALDH1A1LMNA | |
| SCHEMBL28520778 | 0.80 | PDK1 (0.41) | KDM4EPDK1ACKR3ALDH1A1LMNA | |
| SCHEMBL21070432 | 0.80 | PDK1 (0.41) | KDM4EPDK1ACKR3ALDH1A1LMNA | |
| SCHEMBL571075 | 0.79 | PDK1 (0.61) | PDK1 | |
| SCHEMBL2934637 | 0.79 | PDK1 (0.61) | PDK1 | |
| SCHEMBL3029708 | 0.79 | PDK1 (0.61) | PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467369-B | Biaryl amide compounds as kinase inhibitors | 诺华股份有限公司 | 2021-08-20 | — | — | CN | disclosed |