Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 7/20 | 0.61 |
| ▸ | CTSV | O60911 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | TDP2 | O95551 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CASP9 | P55211 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639160 | 0.86 | TNKS (0.63) | TNKSCTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL828493 | 0.86 | TNKS (0.63) | TNKSCTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL28624953 | 0.83 | PARP1 (0.61) | TNKSKDM4EALDH1A1HPGDGAA | |
| SCHEMBL28924699 | 0.83 | TNKS (0.65) | TNKSCTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL16578791 | 0.83 | TNKS (0.61) | TNKSKDM4EALDH1A1HPGDGAA | |
| SCHEMBL311943 | 0.83 | TNKS (0.61) | TNKSKDM4EALDH1A1HPGDGAA | |
| SCHEMBL4774571 | 0.83 | TNKS (0.61) | TNKSKDM4EALDH1A1HPGDGAA | |
| SCHEMBL30161077 | 0.83 | TNKS (0.65) | TNKSCTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL30160913 | 0.83 | PARP1 (0.61) | TNKSKDM4EALDH1A1HPGDGAA | |
| SCHEMBL4763725 | 0.83 | TNKS (0.64) | TNKSKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041257-B | Method for synthesizing indene spiro indene [1,2-c ] isoquinoline triketone compound | 河南师范大学 | 2021-08-03 | — | — | CN | disclosed |