SCHEMBL28629611

SCHEMBL28629611

CC(C)(C)[Si](C)(C)OC1CC(C=O)(OC(N)=O)C1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28645336 0.77 PPM1D (0.38) PPM1D
SCHEMBL28638728 0.75 PPM1D (0.34) PPM1D
SCHEMBL22362807 0.71 PPM1D (0.35) PPM1D
SCHEMBL5205218 0.69 PPM1D (0.42) PPM1D
SCHEMBL29209911 0.69 PPM1D (0.38) PPM1D
SCHEMBL12543318 0.68 PPM1D (0.44) PPM1D
SCHEMBL22380394 0.68 MEN1 (0.35) PPM1D
SCHEMBL28574711 0.67 PPM1D (0.36) PPM1D
SCHEMBL28583173 0.67 PPM1D (0.36) PPM1D
SCHEMBL23704804 0.67 PPM1D (0.37) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454077-A Amide derivatives for the treatment of HBV infection or HBV-induced diseases 爱尔兰詹森科学公司 2021-09-28 CN disclosed