Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 15/20 | 0.59 |
| ▸ | EGFR | P00533 | 5/20 | 0.59 |
| ▸ | SRC | P12931 | 5/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | ABL2 | P42684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629639 | 1.00 | ERBB2 (0.59) | ERBB2EGFRSRCJAK3ERBB4 | |
| SCHEMBL28645350 | 0.88 | ERBB2 (0.76) | ERBB2EGFRJAK3ERBB4 | |
| SCHEMBL28645353 | 0.88 | ERBB2 (0.76) | ERBB2EGFRJAK3ERBB4 | |
| SCHEMBL29926821 | 0.86 | RET (0.58) | ERBB2EGFRSRCABL1ABL2 | |
| SCHEMBL29926948 | 0.82 | ERBB2 (0.54) | ERBB2EGFRSRCJAK3ERBB4 | |
| SCHEMBL28630033 | 0.82 | ERBB2 (0.54) | ERBB2EGFRSRCJAK3ERBB4 | |
| SCHEMBL28630028 | 0.82 | ERBB2 (0.54) | ERBB2EGFRSRCJAK3ERBB4 | |
| SCHEMBL29926654 | 0.79 | SRC (0.66) | EGFRSRCABL1ABL2 | |
| SCHEMBL28627632 | 0.79 | SRC (0.66) | EGFRSRCABL1ABL2 | |
| SCHEMBL28627629 | 0.79 | SRC (0.66) | EGFRSRCABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336760-B | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-113336760-A | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |