Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 13/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | RET | P07949 | 7/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926948 | 1.00 | ERBB2 (0.54) | ERBB2EGFRRETLCKSRC | |
| SCHEMBL28630028 | 1.00 | ERBB2 (0.54) | ERBB2EGFRRETLCKSRC | |
| SCHEMBL30244942 | 0.85 | ERBB2 (0.71) | ERBB2EGFRJAK3ERBB4 | |
| SCHEMBL28902625 | 0.85 | RET (0.62) | ERBB2RETLCKSRC | |
| SCHEMBL29926832 | 0.85 | RET (0.62) | ERBB2RETLCKSRC | |
| SCHEMBL28923114 | 0.85 | RET (0.62) | ERBB2RETLCKSRC | |
| SCHEMBL28645353 | 0.83 | ERBB2 (0.76) | ERBB2EGFRJAK3ERBB4 | |
| SCHEMBL28645350 | 0.83 | ERBB2 (0.76) | ERBB2EGFRJAK3ERBB4 | |
| SCHEMBL28629640 | 0.82 | ERBB2 (0.59) | ERBB2EGFRSRCJAK3ERBB4 | |
| SCHEMBL28629639 | 0.82 | ERBB2 (0.59) | ERBB2EGFRSRCJAK3ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336760-B | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-113336760-A | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |