Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624609 | 0.91 | SCN9A (0.48) | CYP2C9SCN9AALDH1A1GAAMEN1 | |
| SCHEMBL28623383 | 0.86 | KMT2A (0.44) | PIK3CDPIK3CASCN9AALDH1A1MEN1 | |
| SCHEMBL17276259 | 0.85 | CYP2C9 (0.55) | CYP2C9PIK3CDALDH1A1MEN1POLB | |
| SCHEMBL28629242 | 0.82 | CYP2C9 (0.50) | CYP2C9GAA | |
| SCHEMBL28617165 | 0.77 | SCN9A (0.51) | SCN9AALDH1A1MEN1KMT2AERAP1 | |
| SCHEMBL21382774 | 0.77 | CYP2C9 (0.65) | CYP2C9SCN9AALDH1A1MEN1POLB | |
| SCHEMBL19859211 | 0.76 | SCN9A (0.52) | CYP2C9SCN9AALDH1A1MEN1KMT2A | |
| SCHEMBL22226918 | 0.76 | USP30 (0.48) | CYP2C9PIK3CDSCN9AALDH1A1BRD4 | |
| SCHEMBL28624625 | 0.75 | GAA (0.47) | CYP2C9GAA | |
| SCHEMBL28615356 | 0.74 | CNR1 (0.49) | CYP2C9GAAKMT2AERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |