Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629897 | 0.91 | CYP2C9 (0.50) | SCN9ACYP2C9GAAERAP2ERAP1 | |
| SCHEMBL28617165 | 0.86 | SCN9A (0.51) | SCN9AERAP1SCN5ANPC1RAB9A | |
| SCHEMBL19859211 | 0.85 | SCN9A (0.52) | SCN9ACYP2C9NPC1KDM4ERAB9A | |
| SCHEMBL22226918 | 0.84 | USP30 (0.48) | SCN9ACYP2C9NPC1KDM4ERAB9A | |
| SCHEMBL28624625 | 0.82 | GAA (0.47) | CYP2C9GAAKDM4ESMN1; SMN2 | |
| SCHEMBL28615356 | 0.80 | CNR1 (0.49) | CYP2C9GAAERAP2ERAP1KMT2A | |
| SCHEMBL22226442 | 0.80 | HPGD (0.52) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL24099926 | 0.79 | HPGD (0.54) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL22227079 | 0.79 | ALDH1A1 (0.49) | SCN9ACYP2C9NPC1KDM4ERAB9A | |
| SCHEMBL23618981 | 0.78 | SCN9A (0.47) | SCN9ACYP2C9SCN5AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |