Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625222 | 1.00 | MAOB (0.54) | MAOBALDH1A1PAMKMT2AMEN1 | |
| SCHEMBL29021112 | 0.85 | RAB9A (0.56) | MAOBALDH1A1PAMKMT2AMEN1 | |
| SCHEMBL29021113 | 0.85 | RAB9A (0.56) | MAOBALDH1A1PAMKMT2AMEN1 | |
| SCHEMBL28857492 | 0.85 | MAOB (0.53) | MAOBALDH1A1PAMKMT2AMEN1 | |
| SCHEMBL5158237 | 0.84 | MAOB (0.49) | MAOBALDH1A1PAMNPC1RAB9A | |
| SCHEMBL8467720 | 0.84 | MAOB (0.49) | MAOBALDH1A1PAMNPC1RAB9A | |
| SCHEMBL5152333 | 0.82 | MAOB (0.57) | MAOBPAMKMT2ANPC1GLA | |
| SCHEMBL8261373 | 0.82 | MAOB (0.57) | MAOBPAMKMT2ANPC1GLA | |
| SCHEMBL1694508 | 0.82 | MAOB (0.61) | MAOBALDH1A1PAMKMT2AMEN1 | |
| SCHEMBL10619606 | 0.82 | MAOB (0.61) | MAOBALDH1A1PAMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277963-B | Amine compound and preparation method and application thereof | 南京工业大学 | 2022-11-04 | — | — | CN | claimed |
| CN-113277963-A | Amine compound and preparation method and application thereof | 南京工业大学 | 2021-08-20 | — | — | CN | disclosed |