Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.34 |
| ▸ | FEN1 | P39748 | 5/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620253 | 0.85 | ALOX5AP (0.34) | ALOX5APFEN1F2RL1DGAT1EGFR | |
| SCHEMBL29913954 | 0.85 | ALOX5AP (0.34) | ALOX5APFEN1F2RL1DGAT1EGFR | |
| SCHEMBL29198324 | 0.83 | DGAT1 (0.33) | ALOX5APFEN1F2RL1DGAT1EGFR | |
| SCHEMBL23620326 | 0.83 | ALOX5AP (0.33) | ALOX5APFEN1F2RL1DGAT1 | |
| SCHEMBL29913956 | 0.83 | ALOX5AP (0.33) | ALOX5APFEN1F2RL1DGAT1 | |
| SCHEMBL29198325 | 0.82 | ALOX5AP (0.32) | ALOX5APFEN1DGAT1 | |
| SCHEMBL29198334 | 0.82 | ALOX5AP (0.32) | ALOX5APFEN1DGAT1 | |
| SCHEMBL31303180 | 0.81 | ALOX5AP (0.31) | ALOX5APFEN1F2RL1DGAT1 | |
| SCHEMBL23620343 | 0.80 | DGAT1 (0.35) | ALOX5APFEN1DGAT1EGFRIGF1R | |
| SCHEMBL24723932 | 0.80 | JAK1 (0.31) | ALOX5APFEN1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075200-A | JAK inhibitor compounds for the treatment of severe pneumonia | 河南迈英诺医药科技有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-113563345-A | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-111606908-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-111606908-A | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |