Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 16/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 16/20 | 0.50 |
| ▸ | GABRD | O14764 | 13/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 13/20 | 0.50 |
| ▸ | GABRP | O00591 | 10/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.50 |
| ▸ | GABRE | P78334 | 10/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26494438 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL28630492 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL22072577 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL25052039 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL22033310 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL25050361 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL22033309 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL25050363 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL22072575 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP | |
| SCHEMBL26494441 | 1.00 | GABRA1 (0.50) | GABRA1GABRB2GABRDGABRA4GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113383004-A | Neuroactive steroids and methods of use thereof | 萨奇治疗股份有限公司 | 2021-09-10 | — | — | CN | disclosed |