Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634248 | 0.83 | PDE4D (0.44) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL21157504 | 0.83 | PDE4D (0.44) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL21158083 | 0.83 | PDE4D (0.44) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL28561966 | 0.82 | KMT2A (0.47) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL21157492 | 0.81 | POLB (0.41) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL29898969 | 0.81 | POLB (0.41) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL22121068 | 0.78 | KMT2A (0.42) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL30803074 | 0.76 | PARP15 (0.46) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL28308732 | 0.76 | PARP15 (0.46) | KMT2APOLBLMNASMN1; SMN2MAPT | |
| SCHEMBL19436450 | 0.76 | MAPT (0.50) | KMT2APOLBLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016025-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-08-06 | — | — | CN | disclosed |