Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 16/20 | 0.44 |
| ▸ | PDE4A | P27815 | 9/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21157504 | 1.00 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL28634248 | 1.00 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL21157492 | 0.91 | POLB (0.41) | PDE4BLMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL29898969 | 0.91 | POLB (0.41) | PDE4BLMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL3492009 | 0.84 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL28630499 | 0.83 | KMT2A (0.42) | LMNAPOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL28552449 | 0.80 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CMAPT | |
| SCHEMBL21158078 | 0.76 | LMNA (0.41) | LMNAPOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30803028 | 0.76 | LMNA (0.41) | LMNAPOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL3798842 | 0.76 | CASP6 (0.52) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016025-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| WO-2019134705-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |