SCHEMBL28630653

SCHEMBL28630653

N#CCCc1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.50
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
MAPK1 P28482 1/20 0.48
CYP2C19 P33261 1/20 0.48
CHEK1 O14757 1/20 0.43
DAO P14920 1/20 0.43
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
PYCR1 P32322 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CNR1 P21554 1/20 0.41
GPR84 Q9NQS5 1/20 0.40
GGPS1 O95749 1/20 0.40
HTT P42858 1/20 0.40
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4002763 0.81 CYP3A4 (0.43) IDO1CYP1A2CYP3A4MAPK1CYP2C19
SCHEMBL16992744 0.81 FFAR1 (0.42) IDO1CHEK1MEN1KMT2ATP53
SCHEMBL586216 0.81 MEN1 (0.42) IDO1CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL11621292 0.80 IDO1 (0.65) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL4773313 0.80 IDO1 (0.50) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL29457615 0.79 CYP1A2 (0.57) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL549082 0.79 CYP1A2 (0.57) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL11858030 0.77 IDO1 (0.43) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL12875819 0.77 LMNA (0.41) CHEK1MEN1KMT2A
SCHEMBL587015 0.77 PTGES2 (0.45) CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113387891-A Synthesis process of high-purity oxiconazole nitrate 湖南中威制药有限公司 2021-09-14 CN disclosed