Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183674 | 0.93 | TSHR (0.51) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27818214 | 0.87 | BCL9 (0.62) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1429398 | 0.84 | TSHR (0.54) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11725640 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28474988 | 0.83 | TSHR (0.53) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27775918 | 0.82 | NPC1 (0.50) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31255362 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27798824 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27872409 | 0.79 | MAPT (0.44) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11228420 | 0.79 | TSHR (0.49) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |