Methacrylic Acid

Methacrylic Acid

SCHEMBL28630730

C=C(C)C(=O)O.CCCC(C)CC(C)(O)O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TET2 Q6N021 1/20 0.32
ACE2 Q9BYF1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28626224 0.82 TSHR (0.48) TSHR
Methacrylic Acid SCHEMBL7941584 0.77 TSHR (0.62) TSHRCHRM1AKR1A1CHRM3HTR2A
Methacrylic Acid SCHEMBL31589114 0.74 TDP1 (0.42) TSHRCHRM1AKR1A1CHRM3HTR2A
Methacrylic Acid SCHEMBL28105474 0.74 TET2 (0.38) TSHRCHRM1AKR1A1CHRM3HTR2A
Methacrylic Acid SCHEMBL27402548 0.74 TET2 (0.43) TSHRCHRM1ADRA1ATDP1TET2
Methacrylic Acid SCHEMBL2234573 0.74 TET2 (0.43) TSHRCHRM1ADRA1ATDP1TET2
Methacrylic Acid SCHEMBL28304977 0.74 TET2 (0.43) TSHRCHRM1ADRA1ATDP1TET2
SCHEMBL1784146 0.73 TSHR (0.39) TSHRCHRM1AKR1A1CHRM3HTR2A
Methacrylic Acid SCHEMBL2551832 0.72 CHRM1 (0.41) TSHRCHRM1AKR1A1CHRM3HTR2A
Methacrylic Acid SCHEMBL15821451 0.72 CHRM1 (0.41) TSHRCHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113347950-A Ophthalmic lenses, pharmaceutical compositions and uses thereof 红婴生物科技股份有限公司 2021-09-03 CN disclosed