Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL5145666 | 0.89 | TSHR (0.44) | TSHRTDP1TGFBR1ACE2 | |
| Methacrylic Acid SCHEMBL4526194 | 0.89 | TSHR (0.44) | TSHRTDP1TGFBR1ACE2 | |
| Methacrylic Acid SCHEMBL9779579 | 0.84 | TGFBR1 (0.43) | TSHRTDP1TGFBR1ALDH1A1 | |
| Methacrylic Acid SCHEMBL9779254 | 0.84 | TGFBR1 (0.43) | TSHRTDP1TGFBR1ALDH1A1 | |
| Methacrylic Acid SCHEMBL3319371 | 0.84 | TGFBR1 (0.43) | TSHRTDP1TGFBR1ALDH1A1 | |
| Methacrylic Acid SCHEMBL9779539 | 0.84 | TGFBR1 (0.43) | TSHRTDP1TGFBR1ALDH1A1 | |
| Methacrylic Acid SCHEMBL8956036 | 0.81 | CHRM1 (0.39) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| Methacrylic Acid SCHEMBL31589114 | 0.80 | TDP1 (0.42) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| Methacrylic Acid SCHEMBL9779314 | 0.79 | CHRM1 (0.38) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| Methacrylic Acid SCHEMBL21837318 | 0.79 | CHRM1 (0.38) | TSHRCHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248842-B1 | CROSSLINKED POLYMER | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2001-06-19 | — | — | US | disclosed |