Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 9/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630897 | 1.00 | HPGDS (0.48) | HPGDSSYKMAP4K4HDAC4STAMBP | |
| SCHEMBL23796189 | 0.89 | HPGDS (0.60) | HPGDSSTAMBPCOPS5GABRA5HDAC3 | |
| SCHEMBL25070926 | 0.83 | HSP90AA1 (0.44) | HPGDSSYKHDAC1HDAC6MEN1 | |
| SCHEMBL23796218 | 0.81 | HPGDS (0.50) | HPGDSGABRA5MEN1KMT2A | |
| SCHEMBL30301864 | 0.80 | HPGDS (0.43) | HPGDSSYKMAP4K4HDAC4GABRA5 | |
| SCHEMBL30301861 | 0.80 | HPGDS (0.43) | HPGDSSYKMAP4K4HDAC4GABRA5 | |
| SCHEMBL24800517 | 0.80 | HPGDS (0.43) | HPGDSSYKMAP4K4HDAC4HDAC6 | |
| SCHEMBL24800518 | 0.80 | HPGDS (0.43) | HPGDSSYKMAP4K4HDAC4GABRA5 | |
| SCHEMBL30301828 | 0.80 | HPGDS (0.43) | HPGDSSYKMAP4K4HDAC4HDAC6 | |
| SCHEMBL24801197 | 0.80 | HPGDS (0.45) | HPGDSSYKMAP4K4HDAC4STAMBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302175-A | Bicyclic compounds | 维瓦斯治疗公司 | 2021-08-24 | — | — | CN | disclosed |