Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.75 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.62 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056711 | 1.00 | ROCK2 (0.75) | ROCK2ROCK1MYLK4 | |
| SCHEMBL113081 | 0.90 | ROCK2 (0.74) | ROCK2ROCK1MYLK4 | |
| SCHEMBL115008 | 0.88 | ROCK2 (0.76) | ROCK2ROCK1MYLK4 | |
| SCHEMBL21774951 | 0.88 | ROCK2 (0.76) | ROCK2ROCK1MYLK4 | |
| SCHEMBL30518356 | 0.86 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL16042678 | 0.86 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL16041166 | 0.86 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL29478441 | 0.86 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL29478448 | 0.86 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| SCHEMBL16041168 | 0.86 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109528721-B | Combination therapy | 爱瑞制药公司 | 2021-10-01 | — | — | CN | disclosed |