SCHEMBL28631827

SCHEMBL28631827

CCOC=NNC(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.53
CYP1A2 P05177 4/20 0.51
MIF P14174 1/20 0.50
SMN1; SMN2 Q16637 8/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
RAB9A P51151 5/20 0.46
NPC1 O15118 4/20 0.46
ALDH1A1 P00352 4/20 0.46
LMNA P02545 3/20 0.46
CYP2C19 P33261 2/20 0.46
POLB P06746 3/20 0.45
MAPT P10636 3/20 0.44
HTT P42858 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17577099 1.00 GAA (0.53) GAACYP1A2MIFSMN1; SMN2L3MBTL1
SCHEMBL11971336 0.86 LMNA (0.46) GAACYP1A2MIFSMN1; SMN2L3MBTL1
SCHEMBL2378467 0.86 LMNA (0.46) GAACYP1A2MIFSMN1; SMN2L3MBTL1
SCHEMBL17621317 0.86 LMNA (0.46) GAACYP1A2MIFSMN1; SMN2L3MBTL1
SCHEMBL3063339 0.83
SCHEMBL16196894 0.83
SCHEMBL3063335 0.83
SCHEMBL14196325 0.79
SCHEMBL4660002 0.78 GAA (0.54) GAACYP1A2MIFSMN1; SMN2L3MBTL1
SCHEMBL23131067 0.76 GAA (0.57) GAACYP1A2MIFSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113330001-A 3, 3-difluoroallylamine or salt thereof and pharmaceutical composition containing same 柳韩洋行 2021-08-31 CN disclosed