Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618086 | 0.89 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL15110981 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL28646026 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL2594514 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7406263 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL4721794 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL855435 | 0.83 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL15111012 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL30322878 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6121694 | 0.81 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461635-A | 4- (2-chloroethyl) thiazole-2-carboxylic acid ethyl ester and preparation method and application thereof | 上海毕得医药科技股份有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-113461635-A | 4- (2-chloroethyl) thiazole-2-carboxylic acid ethyl ester and preparation method and application thereof | 上海毕得医药科技股份有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-113461635-A | 4- (2-chloroethyl) thiazole-2-carboxylic acid ethyl ester and preparation method and application thereof | 上海毕得医药科技股份有限公司 | 2021-10-01 | — | — | CN | disclosed |