Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502289 | 0.85 | KMT2A (0.54) | PARP1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL23407877 | 0.85 | KMT2A (0.48) | PARP1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL18304685 | 0.83 | NPC1 (0.54) | PARP1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL27918862 | 0.83 | KMT2A (0.51) | PARP1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL31205637 | 0.83 | NPC1 (0.54) | PARP1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL30193965 | 0.81 | L3MBTL1 (0.47) | PARP1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL20285817 | 0.81 | NPC1 (0.56) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL31205426 | 0.81 | NPC1 (0.56) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL6056992 | 0.81 | NPC1 (0.56) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL31205812 | 0.81 | NPC1 (0.56) | KMT2AMAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |